Protein diets plan for weight loss
The groups did not differ significantly with respect to diet-related adverse events. ) Full Text of Discussion. Figure 2 Total 24-Hour Urinary Nitrogen Excretion and Changes in Body Weight. The overall study leaders, together with the principal investigator at each study center, designed the study. Thus, we recognized the need for a large trial that would be designed to overcome the limitations of previous trials and that would compare the effects of three principal dietary macronutrients. The principal investigator at each study center collected the local data, which were entered into a data-registration system (EpiData) 12 and transferred to a central data hub. Methods We enrolled overweight adults from eight European countries who had lost at least 8% of their initial body weight with a 3. The crucial question is whether overweight people have a better response in the long term to diets that emphasize a specific macronutrient composition. Methods Study Protocol The study design, methods, and procedures have been described in detail previously. The project staff of the National Heart, Lung, and Blood Institute also participated in the development of the protocol, monitoring of progress, interpretation of results, and critical review of the manuscript. Article Activity 272 articles have cited this article Article The importance of the composition of a diet for the prevention and management of obesity is debated. Figure 2 Mean Changes in Body Weight and Waist Circumference at Various Time Points. Abstract Background The possible advantage for weight loss of a diet that emphasizes protein, fat, or carbohydrates has not been established, and there are few studies that extend beyond 1 year. The participants were offered group and individual instructional sessions for 2 years.
The primary outcome was the change in body weight after 2 years in two-by-two factorial comparisons of low fat versus high fat and average protein versus high protein and in the comparison of highest and lowest carbohydrate content. Conclusions Reduced-calorie diets result in clinically meaningful weight loss regardless of which macronutrients they emphasize. Media in This Article Figure 1 Screening, Randomization, and Follow-up of Study Participants. The diets consisted of similar foods and met guidelines for cardiovascular health. 3-MJ (800-kcal) low-calorie diet. Media in This Article Poll Results Contributors Figure 1 Mean Change in Body Weight and Waist Circumference from Baseline to 2 Years According to Dietary Macronutrient Content. The European Commission Food Quality and Safety Priority of the Sixth Framework Programme (the main sponsor of the study) had no role in the design of the study or in the analysis or interpretation of the data. gov number, NCT00072995. 11 The study was conducted in eight European countries: Denmark, the Netherlands, the United Kingdom, Greece (Crete), Germany, Spain, Bulgaria, and the Czech Republic. Participants were randomly assigned, in a two-by-two factorial design, to one of five ad libitum diets to prevent weight regain over a 26-week period: a low-protein and low-glycemic-index diet, a low-protein and high-glycemic-index diet, a high-protein and low-glycemic-index diet, a high-protein and high-glycemic-index diet, or a control diet. (ClinicalTrials. Participants Our goal was to recruit 800 overweight and obese subjects (400 at each site), of whom about 40% would be men. Abstract Background Studies of weight-control diets that are high in protein or low in glycemic index have reached varied conclusions, probably owing to the fact that the studies had insufficient power. The diets improved lipid-related risk factors and fasting insulin levels. We report here the results of the 26-week weight-maintenance intervention phase of the study.
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